Methylation-associated partial down-regulation of mesothelin causes resistance to anti-mesothelin immunotoxins in a pancreatic cancer cell line. [electronic resource]
Producer: 20160216Description: e0122462 p. digitalISSN:- 1932-6203
- ADP Ribose Transferases -- immunology
- Apoptosis -- drug effects
- Bacterial Toxins -- immunology
- Base Sequence
- Blotting, Western
- Cell Count
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- DNA Methylation
- Drug Resistance, Neoplasm -- physiology
- Exotoxins -- immunology
- Flow Cytometry
- GPI-Linked Proteins -- immunology
- Gene Expression Regulation, Neoplastic -- physiology
- Humans
- Immunoglobulin Variable Region -- immunology
- Immunotoxins -- immunology
- Mesothelin
- Molecular Sequence Data
- Pancreatic Neoplasms -- metabolism
- Real-Time Polymerase Chain Reaction
- Recombinant Proteins -- immunology
- Reverse Transcriptase Polymerase Chain Reaction
- Sequence Analysis, RNA
- Virulence Factors -- immunology
- Pseudomonas aeruginosa Exotoxin A
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't
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