In vitro and in vivo efficacy of a potent opioid receptor agonist, biphalin, compared to subtype-selective opioid receptor agonists for stroke treatment. [electronic resource]
Producer: 20160120Description: 1-11 p. digitalISSN:- 1872-6240
- 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer -- chemistry
- Analgesics, Opioid -- chemistry
- Brain Edema -- drug therapy
- Brain Infarction -- drug therapy
- Brain Ischemia -- drug therapy
- Cells, Cultured
- Enkephalin, Ala(2)-MePhe(4)-Gly(5)- -- chemistry
- Enkephalin, D-Penicillamine (2,5)- -- chemistry
- Enkephalins -- chemistry
- Glutamic Acid -- toxicity
- Ischemia -- drug therapy
- Motor Activity -- drug effects
- Neurons -- drug effects
- Neuroprotective Agents -- chemistry
- Receptors, Opioid, delta -- agonists
- Receptors, Opioid, kappa -- agonists
- Receptors, Opioid, mu -- agonists
- Reperfusion Injury -- drug therapy
- Severity of Illness Index
- Stroke -- drug therapy
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Publication Type: Comparative Study; Journal Article; Research Support, N.I.H., Extramural
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