Signalling thresholds and negative B-cell selection in acute lymphoblastic leukaemia. [electronic resource]
Producer: 20150702Description: 357-61 p. digitalISSN:- 1476-4687
- Amino Acid Motifs -- genetics
- Animals
- Antigens, CD -- metabolism
- B-Lymphocytes -- drug effects
- Cell Death -- drug effects
- Cell Line, Tumor
- Cell Transformation, Neoplastic
- Disease Models, Animal
- Drug Resistance, Neoplasm -- drug effects
- Enzyme Activation -- drug effects
- Female
- Fusion Proteins, bcr-abl -- genetics
- Gene Deletion
- Humans
- Inositol Polyphosphate 5-Phosphatases
- Intracellular Signaling Peptides and Proteins -- agonists
- Mice
- Mice, Inbred NOD
- Mice, SCID
- Phosphatidylinositol-3,4,5-Trisphosphate 5-Phosphatases
- Phosphoric Monoester Hydrolases -- antagonists & inhibitors
- Platelet Endothelial Cell Adhesion Molecule-1 -- metabolism
- Precursor Cell Lymphoblastic Leukemia-Lymphoma -- drug therapy
- Precursor Cells, B-Lymphoid -- drug effects
- Protein Tyrosine Phosphatase, Non-Receptor Type 6 -- deficiency
- Protein-Tyrosine Kinases -- metabolism
- Receptors, Antigen, B-Cell -- deficiency
- Receptors, Immunologic -- genetics
- Signal Transduction -- drug effects
- Syk Kinase
- Tyrosine -- metabolism
- Xenograft Model Antitumor Assays
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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