Induction of cell cycle arrest and apoptosis by betulinic acid-rich fraction from Dillenia suffruticosa root in MCF-7 cells involved p53/p21 and mitochondrial signalling pathway. [electronic resource]
Producer: 20160107Description: 270-8 p. digitalISSN:- 1872-7573
- Apoptosis -- drug effects
- Apoptosis Regulatory Proteins -- metabolism
- Cell Line, Tumor
- Cyclin-Dependent Kinase Inhibitor p21 -- metabolism
- Dilleniaceae -- chemistry
- G1 Phase Cell Cycle Checkpoints -- drug effects
- Humans
- MCF-7 Cells
- Mitochondria -- drug effects
- Pentacyclic Triterpenes
- Plant Extracts -- chemistry
- Plant Roots -- chemistry
- Protein Processing, Post-Translational -- drug effects
- Proto-Oncogene Proteins c-bcl-2 -- metabolism
- RNA, Messenger -- metabolism
- Resting Phase, Cell Cycle -- drug effects
- Signal Transduction -- drug effects
- Triterpenes -- pharmacology
- Tumor Suppressor Protein p53 -- metabolism
- bcl-2-Associated X Protein -- drug effects
- Betulinic Acid
No physical items for this record
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
There are no comments on this title.
Log in to your account to post a comment.