IDH2 and NPM1 Mutations Cooperate to Activate Hoxa9/Meis1 and Hypoxia Pathways in Acute Myeloid Leukemia. [electronic resource]
Producer: 20150727Description: 2005-16 p. digitalISSN:- 1538-7445
- Animals
- Cell Hypoxia
- Gene Expression Regulation, Leukemic
- Homeodomain Proteins -- metabolism
- Humans
- Isocitrate Dehydrogenase -- genetics
- Leukemia, Myeloid, Acute -- genetics
- Mice, Inbred C57BL
- Mutation, Missense
- Myeloid Ecotropic Viral Integration Site 1 Protein
- Neoplasm Proteins -- metabolism
- Neoplasm Transplantation
- Nuclear Proteins -- genetics
- Nucleophosmin
- Up-Regulation
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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