Caffeic acid phenethyl ester induced cell cycle arrest and growth inhibition in androgen-independent prostate cancer cells via regulation of Skp2, p53, p21Cip1 and p27Kip1. [electronic resource]
Producer: 20160119Description: 6684-707 p. digitalISSN:- 1949-2553
- Animals
- Antineoplastic Agents -- pharmacology
- Antineoplastic Combined Chemotherapy Protocols -- pharmacology
- Caffeic Acids -- pharmacology
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- Cyclin-Dependent Kinase Inhibitor p21 -- genetics
- Cyclin-Dependent Kinase Inhibitor p27 -- genetics
- Dose-Response Relationship, Drug
- Drug Synergism
- G1 Phase Cell Cycle Checkpoints -- drug effects
- G2 Phase Cell Cycle Checkpoints -- drug effects
- Humans
- Male
- Mice, Inbred BALB C
- Mice, Nude
- Phenylethyl Alcohol -- analogs & derivatives
- Phosphatidylinositol 3-Kinase -- metabolism
- Phosphoinositide-3 Kinase Inhibitors
- Phosphorylation
- Prostatic Neoplasms, Castration-Resistant -- drug therapy
- Protein Kinase Inhibitors -- pharmacology
- Proto-Oncogene Proteins c-bcl-2 -- antagonists & inhibitors
- RNA Interference
- S-Phase Kinase-Associated Proteins -- genetics
- Signal Transduction -- drug effects
- Time Factors
- Transfection
- Tumor Burden -- drug effects
- Tumor Suppressor Protein p53 -- genetics
- Xenograft Model Antitumor Assays
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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