First-in-human trial of the safety, pharmacokinetics and immunogenicity of a PEGylated anti-CD40L antibody fragment (CDP7657) in healthy individuals and patients with systemic lupus erythematosus. [electronic resource]
Producer: 20160531Description: 1045-56 p. digitalISSN:- 1477-0962
- Adult
- CD40 Ligand -- antagonists & inhibitors
- Cohort Studies
- Dose-Response Relationship, Immunologic
- Double-Blind Method
- Female
- Humans
- Immunoglobulin Fab Fragments -- administration & dosage
- Immunoglobulin Fragments -- administration & dosage
- Lupus Erythematosus, Systemic -- drug therapy
- Male
- Middle Aged
- Polyethylene Glycols -- administration & dosage
- Treatment Outcome
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Publication Type: Clinical Trial, Phase I; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
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