Design and optimization of topical methotrexate loaded niosomes for enhanced management of psoriasis: application of Box-Behnken design, in-vitro evaluation and in-vivo skin deposition study. [electronic resource]
Producer: 20160115Description: 235-43 p. digitalISSN:- 1873-3476
- Administration, Cutaneous
- Animals
- Area Under Curve
- Chemistry, Pharmaceutical
- Cholesterol -- chemistry
- Dermatologic Agents -- administration & dosage
- Drug Carriers
- Hexoses -- chemistry
- Liposomes
- Male
- Methotrexate -- administration & dosage
- Microscopy, Electron, Transmission
- Models, Statistical
- Nanotechnology
- Organophosphates -- chemistry
- Particle Size
- Psoriasis -- drug therapy
- Rats, Wistar
- Skin -- metabolism
- Skin Absorption
- Solubility
- Surface Properties
- Surface-Active Agents -- chemistry
- Technology, Pharmaceutical -- methods
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Publication Type: Journal Article
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