TRIM26 negatively regulates interferon-β production and antiviral response through polyubiquitination and degradation of nuclear IRF3. [electronic resource]
Producer: 20150731Description: e1004726 p. digitalISSN:- 1553-7374
- Animals
- Blotting, Western
- Cell Nucleus -- metabolism
- Enzyme-Linked Immunosorbent Assay
- Fluorescent Antibody Technique
- Interferon Regulatory Factor-3 -- metabolism
- Interferon-beta -- biosynthesis
- Mice
- Mice, Inbred C57BL
- Mice, Transgenic
- Reverse Transcriptase Polymerase Chain Reaction
- Rhabdoviridae Infections -- immunology
- Transfection
- Tripartite Motif Proteins
- Ubiquitin-Protein Ligases -- metabolism
- Ubiquitination
- Vesiculovirus
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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