TALEN mediated targeted editing of GM2/GD2-synthase gene modulates anchorage independent growth by reducing anoikis resistance in mouse tumor cells. [electronic resource]
Producer: 20151016Description: 9048 p. digitalISSN:- 2045-2322
- Animals
- Anoikis -- genetics
- Base Sequence
- Binding Sites
- Cell Adhesion -- genetics
- Cell Line, Tumor
- Cell Transformation, Neoplastic -- genetics
- DNA End-Joining Repair
- Endonucleases -- genetics
- Gene Expression
- Gene Knockout Techniques
- Gene Targeting
- Mice
- N-Acetylgalactosaminyltransferases -- chemistry
- Neoplasms -- genetics
- Protein Binding
- Tumor Burden
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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