3-(Benzo[d][1,3]dioxol-5-ylamino)-N-(4-fluorophenyl)thiophene-2-carboxamide overcomes cancer chemoresistance via inhibition of angiogenesis and P-glycoprotein efflux pump activity. [electronic resource]
Producer: 20160209Description: 4296-309 p. digitalISSN:- 1477-0539
- ATP Binding Cassette Transporter, Subfamily B -- antagonists & inhibitors
- ATP Binding Cassette Transporter, Subfamily B, Member 1 -- antagonists & inhibitors
- Antineoplastic Agents -- chemistry
- Benzodioxoles -- chemistry
- Cell Line, Tumor
- Drug Resistance, Neoplasm -- drug effects
- Drug Screening Assays, Antitumor
- Humans
- Models, Molecular
- Neovascularization, Pathologic -- drug therapy
- Protein Conformation
- Quinolines -- chemistry
- Structure-Activity Relationship
- Thiophenes -- chemistry
- Vascular Endothelial Growth Factor Receptor-1 -- antagonists & inhibitors
- Vascular Endothelial Growth Factor Receptor-2 -- antagonists & inhibitors
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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