Sirt3-MnSOD axis represses nicotine-induced mitochondrial oxidative stress and mtDNA damage in osteoblasts. [electronic resource]
Producer: 20160119Description: 306-12 p. digitalISSN:- 1745-7270
- Acetylation -- drug effects
- Animals
- Blotting, Western
- Cells, Cultured
- DNA Damage
- DNA, Mitochondrial -- genetics
- Down-Regulation -- drug effects
- Ganglionic Stimulants -- toxicity
- Humans
- Metalloporphyrins -- pharmacology
- Mice, 129 Strain
- Mice, Inbred C57BL
- Mice, Knockout
- Mitochondria -- drug effects
- Nicotine -- toxicity
- Osteoclasts -- cytology
- Oxidative Stress -- drug effects
- Reactive Oxygen Species -- metabolism
- Reverse Transcriptase Polymerase Chain Reaction
- Sirtuin 3 -- genetics
- Superoxide Dismutase -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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