Early secreted antigen ESAT-6 of Mycobacterium Tuberculosis promotes apoptosis of macrophages via targeting the microRNA155-SOCS1 interaction. [electronic resource]
Producer: 20151221Description: 1276-88 p. digitalISSN:- 1421-9778
- Animals
- Antigens, Bacterial -- genetics
- Apoptosis -- drug effects
- Cell Line
- Humans
- Interleukin-6 -- genetics
- Leukocytes, Mononuclear -- metabolism
- Macrophages -- cytology
- Mice
- MicroRNAs -- metabolism
- Mycobacterium tuberculosis -- metabolism
- RNA Interference
- Recombinant Proteins -- biosynthesis
- Suppressor of Cytokine Signaling Proteins -- genetics
- Toll-Like Receptor 2 -- antagonists & inhibitors
- Transcription Factor RelA -- antagonists & inhibitors
- Tuberculosis -- metabolism
- Tumor Necrosis Factor-alpha -- genetics
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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