Endothelin receptor blockade ameliorates vascular fragility in endothelial cell-specific Fli-1-knockout mice by increasing Fli-1 DNA binding ability. [electronic resource]
Producer: 20150629Description: 1335-44 p. digitalISSN:- 2326-5205
- Actins -- metabolism
- Animals
- Bosentan
- Capillary Permeability
- Cell Line
- Cells, Cultured
- Chromatin Immunoprecipitation
- Endothelial Cells -- metabolism
- Endothelin Receptor Antagonists -- pharmacology
- Endothelin-1 -- metabolism
- Gene Expression
- Humans
- Immunoblotting
- Immunohistochemistry
- Mice
- Mice, Knockout
- Microvessels -- cytology
- Phosphorylation
- Promoter Regions, Genetic
- Protein Kinase C-delta -- metabolism
- Proto-Oncogene Protein c-fli-1 -- genetics
- Proto-Oncogene Proteins c-abl -- metabolism
- RNA, Messenger -- metabolism
- Receptors, Endothelin -- metabolism
- Reverse Transcriptase Polymerase Chain Reaction
- Scleroderma, Systemic -- metabolism
- Sulfonamides -- pharmacology
- Vascular Diseases
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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