Crude extract of Rheum palmatum L. Induces cell cycle arrest S phase and apoptosis through mitochondrial-dependent pathways in U-2 OS human osteosarcoma cells. [electronic resource]
Producer: 20170216Description: 957-69 p. digitalISSN:- 1522-7278
- Antineoplastic Agents, Phytogenic -- pharmacology
- Apoptosis -- drug effects
- Apoptosis Regulatory Proteins -- metabolism
- Bone Neoplasms -- drug therapy
- Calcium Signaling
- Cell Line, Tumor
- Cell Survival -- drug effects
- DNA Damage
- Drug Screening Assays, Antitumor
- Drugs, Chinese Herbal -- pharmacology
- Endoplasmic Reticulum Chaperone BiP
- Humans
- Membrane Potential, Mitochondrial -- drug effects
- Mitochondria -- drug effects
- Osteosarcoma -- drug therapy
- Protein Transport
- Reactive Oxygen Species -- metabolism
- Rheum -- chemistry
- S Phase Cell Cycle Checkpoints -- drug effects
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Publication Type: Journal Article
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