Anti-dsDNA antibody induces soluble fibronectin secretion by proximal renal tubular epithelial cells and downstream increase of TGF-β1 and collagen synthesis. [electronic resource]
Producer: 20160114Description: 111-22 p. digitalISSN:- 1095-9157
- Antibodies, Antinuclear -- immunology
- Antibodies, Blocking -- immunology
- Cells, Cultured
- Collagen -- biosynthesis
- DNA -- immunology
- Epithelial Cells -- drug effects
- Extracellular Signal-Regulated MAP Kinases -- metabolism
- Fibronectins -- genetics
- Fibrosis
- Humans
- Kidney Tubules, Proximal -- immunology
- Lupus Nephritis -- drug therapy
- Mycophenolic Acid -- pharmacology
- Protein Kinase C -- metabolism
- Signal Transduction -- drug effects
- Transforming Growth Factor beta1 -- biosynthesis
- Up-Regulation
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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