Polypeptide-based nanogels co-encapsulating a synergistic combination of doxorubicin with 17-AAG show potent anti-tumor activity in ErbB2-driven breast cancer models. [electronic resource]
Producer: 20160203Description: 59-66 p. digitalISSN:- 1873-4995
- Animals
- Anti-Bacterial Agents -- administration & dosage
- Benzoquinones -- administration & dosage
- Breast Neoplasms -- drug therapy
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- Chemistry, Pharmaceutical
- Doxorubicin -- administration & dosage
- Drug Compounding
- Drug Synergism
- Female
- Gels
- HSP90 Heat-Shock Proteins -- antagonists & inhibitors
- Humans
- Lactams, Macrocyclic -- administration & dosage
- Mice
- Mice, Nude
- Nanostructures -- chemistry
- Receptor, ErbB-2 -- genetics
- Xenograft Model Antitumor Assays
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
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