Stabilizing a flexible interdomain hinge region harboring the SMB binding site drives uPAR into its closed conformation. [electronic resource]
Producer: 20150519Description: 1389-1403 p. digitalISSN:- 1089-8638
- Amino Acid Sequence
- Antibodies, Monoclonal -- immunology
- Binding Sites
- Cell Adhesion
- Crystallography, X-Ray
- Epitope Mapping
- Humans
- Kinetics
- Ligands
- Models, Molecular
- Molecular Sequence Data
- Protein Conformation
- Protein Structure, Tertiary
- Pseudopodia -- metabolism
- Receptors, Urokinase Plasminogen Activator -- chemistry
- Sequence Homology, Amino Acid
- Signal Transduction
- Somatomedins -- metabolism
- Surface Plasmon Resonance
- Urokinase-Type Plasminogen Activator -- metabolism
- Vitronectin -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
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