Evaluation of metabolism dependent inhibition of CYP2B6 mediated bupropion hydroxylation in human liver microsomes by monoamine oxidase inhibitors and prediction of potential as perpetrators of drug interaction. [electronic resource]
Producer: 20150625Description: 9-20 p. digitalISSN:- 1872-7786
- Bupropion -- metabolism
- Clorgyline -- pharmacology
- Cytochrome P-450 CYP2B6 -- metabolism
- Cytochrome P-450 CYP2B6 Inhibitors -- pharmacology
- Drug Interactions
- Glutathione -- metabolism
- Humans
- Hydroxylation
- Inhibitory Concentration 50
- Kinesics
- Microsomes, Liver -- drug effects
- Monoamine Oxidase Inhibitors -- chemistry
- Pargyline -- pharmacology
- Phenelzine -- pharmacology
- Selegiline -- pharmacology
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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