CYP3A5 Functions as a Tumor Suppressor in Hepatocellular Carcinoma by Regulating mTORC2/Akt Signaling. [electronic resource]
Producer: 20160123Description: 1470-81 p. digitalISSN:- 1538-7445
- Animals
- Carcinoma, Hepatocellular -- enzymology
- Cell Movement
- Cytochrome P-450 CYP3A -- physiology
- Down-Regulation
- Gene Expression Regulation, Neoplastic
- Genes, Tumor Suppressor
- Humans
- Kaplan-Meier Estimate
- Liver Neoplasms -- enzymology
- Lung Neoplasms -- enzymology
- Mechanistic Target of Rapamycin Complex 2
- Mice, Nude
- Multiprotein Complexes -- metabolism
- Neoplasm Invasiveness
- Neoplasm Transplantation
- Prognosis
- Proportional Hazards Models
- Protein Processing, Post-Translational
- Proto-Oncogene Proteins c-akt -- metabolism
- Signal Transduction
- TOR Serine-Threonine Kinases -- metabolism
- Tissue Inhibitor of Metalloproteinase-1 -- genetics
- Tissue Inhibitor of Metalloproteinase-2 -- genetics
- Transcriptional Activation
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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