Design and synthesis of new bioisosteres of spirooxindoles (MI-63/219) as anti-breast cancer agents. [electronic resource]
Producer: 20151005Description: 839-48 p. digitalISSN:- 1464-3391
- Animals
- Antineoplastic Agents -- chemistry
- Breast -- drug effects
- Breast Neoplasms -- drug therapy
- Cell Line, Tumor
- Drug Design
- Female
- Humans
- Indoles -- chemistry
- Mice, Nude
- Oxindoles
- Protein Interaction Maps -- drug effects
- Proto-Oncogene Proteins c-mdm2 -- antagonists & inhibitors
- Spiro Compounds -- chemistry
- Tumor Suppressor Protein p53 -- antagonists & inhibitors
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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