Cationic nanocarriers induce cell necrosis through impairment of Na(+)/K(+)-ATPase and cause subsequent inflammatory response. [electronic resource]
Producer: 20160418Description: 237-53 p. digitalISSN:- 1748-7838
- Animals
- Apoptosis -- drug effects
- Cations -- chemistry
- Cell Line, Tumor
- Chitosan -- chemistry
- DNA, Mitochondrial -- metabolism
- Drug Carriers -- chemistry
- Humans
- Inflammation -- pathology
- Liposomes -- chemistry
- Mice
- Mice, Inbred C57BL
- Mice, Knockout
- Mitochondria -- drug effects
- Myeloid Differentiation Factor 88 -- metabolism
- Nanostructures -- chemistry
- Necrosis
- Ouabain -- pharmacology
- Polyethyleneimine -- chemistry
- Signal Transduction -- drug effects
- Sodium-Potassium-Exchanging ATPase -- antagonists & inhibitors
- Toll-Like Receptor 9 -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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