Celastrol induces apoptosis and autophagy via the ROS/JNK signaling pathway in human osteosarcoma cells: an in vitro and in vivo study. [electronic resource]
Producer: 20150911Description: e1604 p. digitalISSN:- 2041-4889
- Animals
- Apoptosis -- drug effects
- Autophagy -- drug effects
- Caspases -- metabolism
- Cell Cycle Checkpoints -- drug effects
- Cell Cycle Proteins -- metabolism
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- Enzyme Activation -- drug effects
- Female
- Fibroblasts -- drug effects
- Humans
- JNK Mitogen-Activated Protein Kinases -- metabolism
- MAP Kinase Signaling System -- drug effects
- Mice, Inbred BALB C
- Mice, Nude
- Mitochondria -- drug effects
- Models, Biological
- Osteosarcoma -- enzymology
- Pentacyclic Triterpenes
- Phagosomes -- drug effects
- Reactive Oxygen Species -- metabolism
- Triterpenes -- pharmacology
- Xenograft Model Antitumor Assays
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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