Potency enhancement of the κ-opioid receptor antagonist probe ML140 through sulfonamide constraint utilizing a tetrahydroisoquinoline motif. [electronic resource]
Producer: 20160321Description: 3948-56 p. digitalISSN:- 1464-3391
- Animals
- Arrestins -- metabolism
- Benzamides -- chemistry
- CHO Cells
- Chemistry Techniques, Synthetic
- Cricetulus
- Drug Evaluation, Preclinical -- methods
- Guanosine 5'-O-(3-Thiotriphosphate) -- metabolism
- Humans
- Naltrexone -- analogs & derivatives
- Narcotic Antagonists -- chemistry
- Receptors, Opioid, kappa -- antagonists & inhibitors
- Structure-Activity Relationship
- Sulfonamides -- chemistry
- Tetrahydroisoquinolines -- chemistry
- beta-Arrestins
No physical items for this record
Publication Type: Journal Article; Research Support, N.I.H., Extramural
There are no comments on this title.
Log in to your account to post a comment.