Inflammatory cytokine TSLP stimulates platelet secretion and potentiates platelet aggregation via a TSLPR-dependent PI3K/Akt signaling pathway. [electronic resource]
Producer: 20150910Description: 160-74 p. digitalISSN:- 1421-9778
- Androstadienes -- pharmacology
- Animals
- Blood Platelets -- drug effects
- Carotid Artery Thrombosis -- chemically induced
- Chlorides -- toxicity
- Chromones -- pharmacology
- Cytokines -- pharmacology
- Disease Models, Animal
- Ferric Compounds -- toxicity
- Humans
- Immunoglobulins -- deficiency
- Mice
- Mice, Inbred C57BL
- Mice, Knockout
- Morpholines -- pharmacology
- P-Selectin -- metabolism
- Phosphatidylinositol 3-Kinases -- metabolism
- Phosphoinositide-3 Kinase Inhibitors
- Phosphorylation -- drug effects
- Platelet Activation -- drug effects
- Platelet Aggregation -- drug effects
- Platelet Glycoprotein GPIIb-IIIa Complex -- metabolism
- Proto-Oncogene Proteins c-akt -- metabolism
- Receptors, Cytokine -- deficiency
- Signal Transduction -- drug effects
- Wortmannin
- Thymic Stromal Lymphopoietin
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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