Metformin and Rapamycin Reduce Pancreatic Cancer Growth in Obese Prediabetic Mice by Distinct MicroRNA-Regulated Mechanisms. [electronic resource]
Producer: 20150629Description: 1632-42 p. digitalISSN:- 1939-327X
- Animals
- Body Weight
- Cell Cycle -- drug effects
- Diet, Diabetic
- Energy Intake
- Glucose Intolerance
- Hypoglycemic Agents -- therapeutic use
- Immunosuppressive Agents -- therapeutic use
- Male
- Metformin -- therapeutic use
- Mice
- Mice, Inbred C57BL
- Mice, Obese
- MicroRNAs -- genetics
- Neoplasms, Experimental -- drug therapy
- Pancreatic Neoplasms -- drug therapy
- Prediabetic State -- drug therapy
- Random Allocation
- Sirolimus -- therapeutic use
- Snail Family Transcription Factors
- Transcription Factors -- genetics
- Vimentin -- genetics
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Publication Type: Journal Article; Research Support, N.I.H., Extramural
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