Lipopolysaccharide (LPS)-mediated angiopoietin-2-dependent autocrine angiogenesis is regulated by NADPH oxidase 2 (Nox2) in human pulmonary microvascular endothelial cells. [electronic resource]
Producer: 20150511Description: 5449-61 p. digitalISSN:- 1083-351X
- Active Transport, Cell Nucleus -- drug effects
- Angiopoietin-2 -- genetics
- Animals
- Cells, Cultured
- Endothelial Cells -- drug effects
- Gene Expression -- drug effects
- Humans
- I-kappa B Kinase -- metabolism
- Immunoblotting
- Lipopolysaccharides -- pharmacology
- Lung -- blood supply
- Membrane Glycoproteins -- genetics
- Mice, Inbred C57BL
- Microscopy, Fluorescence
- Microvessels -- cytology
- NADPH Oxidase 2
- NADPH Oxidases -- genetics
- NF-kappa B -- metabolism
- Neovascularization, Physiologic -- drug effects
- Phosphorylation -- drug effects
- RNA Interference
- Receptor, TIE-2 -- genetics
- Reverse Transcriptase Polymerase Chain Reaction
- Signal Transduction -- drug effects
- Transcription Factor AP-1 -- metabolism
- Vascular Endothelial Growth Factor A -- genetics
- p38 Mitogen-Activated Protein Kinases -- metabolism
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Publication Type: Journal Article; Research Support, N.I.H., Extramural
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