Oxidative stress activates endothelial innate immunity via sterol regulatory element binding protein 2 (SREBP2) transactivation of microRNA-92a. [electronic resource]
Producer: 20150504Description: 805-14 p. digitalISSN:- 1524-4539
- Aged
- Angiotensin II -- toxicity
- Animals
- Coronary Disease -- blood
- Endothelial Cells -- metabolism
- Endothelium, Vascular -- metabolism
- Female
- Free Radical Scavengers -- pharmacology
- Gene Expression Regulation
- Genes, Reporter
- HEK293 Cells
- Human Umbilical Vein Endothelial Cells
- Humans
- Hydrogen Peroxide -- toxicity
- Hypercholesterolemia -- genetics
- Immunity, Innate -- genetics
- Inflammasomes -- metabolism
- Interleukin-1beta -- blood
- Kruppel-Like Factor 4
- Lipoproteins, LDL -- toxicity
- Male
- Mice
- Mice, Transgenic
- MicroRNAs -- biosynthesis
- Middle Aged
- Organometallic Compounds -- pharmacology
- Oxidative Stress -- genetics
- Recombinant Fusion Proteins -- metabolism
- Salicylates -- pharmacology
- Sterol Regulatory Element Binding Protein 2 -- genetics
- Transcriptional Activation
- Zebrafish
- Zebrafish Proteins -- physiology
No physical items for this record
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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