Virtual high throughput screening of carbapenem derivatives as new generation carbapenemase and penicillin binding protein inhibitors: a hunt to save drug of last resort. [electronic resource]
Producer: 20150923Description: 18-23 p. digitalISSN:- 1875-5402
- Anti-Bacterial Agents -- chemistry
- Bacterial Infections -- drug therapy
- Bacterial Proteins -- antagonists & inhibitors
- Carbapenems -- chemistry
- Computer-Aided Design
- Drug Design
- Drug Evaluation, Preclinical
- Enzyme Inhibitors -- chemistry
- High-Throughput Screening Assays
- Humans
- Klebsiella pneumoniae -- enzymology
- Methicillin-Resistant Staphylococcus aureus -- enzymology
- Molecular Docking Simulation
- Molecular Dynamics Simulation
- Penicillin-Binding Proteins -- antagonists & inhibitors
- beta-Lactamases -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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