Curtailing endothelial TGF-β signaling is sufficient to reduce endothelial-mesenchymal transition and fibrosis in CKD. [electronic resource]
Producer: 20150611Description: 817-29 p. digitalISSN:- 1533-3450
- Animals
- Cell Transdifferentiation
- Endoglin
- Endothelium -- metabolism
- Fibrosis
- Folic Acid
- Intracellular Signaling Peptides and Proteins -- metabolism
- Kidney -- pathology
- Mice, Transgenic
- Neovascularization, Physiologic
- Protein Serine-Threonine Kinases -- genetics
- Receptor, Transforming Growth Factor-beta Type II
- Receptors, Transforming Growth Factor beta -- genetics
- Renal Insufficiency, Chronic -- metabolism
- Smad Proteins -- metabolism
- Transforming Growth Factor beta -- metabolism
- Ureteral Obstruction
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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