A human tRNA synthetase is a potent PARP1-activating effector target for resveratrol. [electronic resource]
Producer: 20150407Description: 370-3 p. digitalISSN:- 1476-4687
- Alternative Splicing
- Animals
- Biocatalysis -- drug effects
- Catalytic Domain
- Cell Nucleus -- enzymology
- Crystallography, X-Ray
- Culture Media, Serum-Free
- Enzyme Activation -- drug effects
- Humans
- Male
- Mice
- Mice, Inbred BALB C
- Models, Molecular
- Poly (ADP-Ribose) Polymerase-1
- Poly Adenosine Diphosphate Ribose -- metabolism
- Poly(ADP-ribose) Polymerases -- chemistry
- Protein Conformation
- Resveratrol
- Signal Transduction -- drug effects
- Sirtuin 1 -- metabolism
- Sirtuins -- metabolism
- Stilbenes -- antagonists & inhibitors
- Tyrosine-tRNA Ligase -- antagonists & inhibitors
No physical items for this record
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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