Inhibition of choroidal fibrovascular membrane formation by new class of RNA interference therapeutic agent targeting periostin. [electronic resource]
Producer: 20150930Description: 127-37 p. digitalISSN:- 1476-5462
- Animals
- Base Sequence
- Cell Adhesion
- Cell Adhesion Molecules -- genetics
- Cell Movement
- Cell Proliferation
- Cells, Cultured
- Choroid -- blood supply
- Choroidal Neovascularization -- therapy
- Gene Knockdown Techniques
- Genetic Therapy
- Humans
- Intravitreal Injections
- Macular Degeneration -- therapy
- Mice, Inbred C57BL
- Mice, Knockout
- Molecular Sequence Data
- RNA Interference
- RNA, Small Interfering -- administration & dosage
- Retinal Pigment Epithelium -- pathology
- Toll-Like Receptor 3 -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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