Suppression of mitochondrial biogenesis through toll-like receptor 4-dependent mitogen-activated protein kinase kinase/extracellular signal-regulated kinase signaling in endotoxin-induced acute kidney injury. [electronic resource]
Producer: 20150708Description: 346-57 p. digitalISSN:- 1521-0103
- Acute Kidney Injury -- chemically induced
- Animals
- DNA, Mitochondrial -- metabolism
- Disease Models, Animal
- Dose-Response Relationship, Drug
- Endotoxins -- toxicity
- Extracellular Signal-Regulated MAP Kinases -- antagonists & inhibitors
- Kidney Cortex -- drug effects
- Kidney Function Tests
- MAP Kinase Signaling System -- drug effects
- Male
- Mice, Inbred C57BL
- Mice, Knockout
- Mitogen-Activated Protein Kinase Kinases -- antagonists & inhibitors
- Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha
- Toll-Like Receptor 4 -- genetics
- Transcription Factors -- antagonists & inhibitors
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Publication Type: Journal Article; Research Support, N.I.H., Extramural
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