Mechanosignaling through YAP and TAZ drives fibroblast activation and fibrosis. [electronic resource]
Producer: 20150410Description: L344-57 p. digitalISSN:- 1522-1504
- Adaptor Proteins, Signal Transducing -- genetics
- Animals
- Cell Cycle Proteins
- Female
- Fibroblasts -- metabolism
- Gene Knockdown Techniques
- Humans
- Intracellular Signaling Peptides and Proteins -- genetics
- Lung -- metabolism
- Male
- Mechanotransduction, Cellular -- genetics
- Mice
- Mice, Inbred NOD
- Mutation
- NIH 3T3 Cells
- Phosphoproteins -- genetics
- Plasminogen Activator Inhibitor 1 -- biosynthesis
- Pulmonary Fibrosis -- genetics
- Serpin E2 -- biosynthesis
- Trans-Activators
- Transcription Factors
- Transcriptional Coactivator with PDZ-Binding Motif Proteins
- Transforming Growth Factor beta -- genetics
- YAP-Signaling Proteins
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Publication Type: Clinical Trial; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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