Hispidulin inhibits proliferation and enhances chemosensitivity of gallbladder cancer cells by targeting HIF-1α. [electronic resource]
Producer: 20150511Description: 236-46 p. digitalISSN:- 1090-2422
- ATP Binding Cassette Transporter, Subfamily B, Member 1 -- metabolism
- Animals
- Antineoplastic Agents -- pharmacology
- Apoptosis
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- Cell Survival -- drug effects
- Deoxycytidine -- analogs & derivatives
- Drug Resistance, Neoplasm
- Drug Synergism
- Female
- Flavones -- pharmacology
- Fluorouracil -- pharmacology
- G1 Phase Cell Cycle Checkpoints
- Gallbladder Neoplasms -- drug therapy
- Gene Expression Regulation, Neoplastic -- drug effects
- Humans
- Hypoxia-Inducible Factor 1, alpha Subunit -- antagonists & inhibitors
- Mice, Inbred BALB C
- Mice, Nude
- Signal Transduction
- Transcriptional Activation -- drug effects
- Tumor Burden -- drug effects
- Xenograft Model Antitumor Assays
- Gemcitabine
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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