GM1 and GD1a gangliosides modulate toxic and inflammatory effects of E. coli lipopolysaccharide by preventing TLR4 translocation into lipid rafts. [electronic resource]
Producer: 20150825Description: 239-47 p. digitalISSN:- 0006-3002
- Animals
- Cattle
- Cell Survival -- drug effects
- Dinoprostone -- antagonists & inhibitors
- Epithelial Cells -- cytology
- Escherichia coli -- chemistry
- G(M1) Ganglioside -- analogs & derivatives
- Gene Expression Regulation
- Lipopolysaccharides -- antagonists & inhibitors
- Male
- Membrane Microdomains -- drug effects
- Nitric Oxide -- antagonists & inhibitors
- Nitric Oxide Synthase Type II -- genetics
- PC12 Cells
- Primary Cell Culture
- Protein Transport
- Rana temporaria
- Rats
- Reactive Oxygen Species -- antagonists & inhibitors
- Signal Transduction
- Toll-Like Receptor 4 -- antagonists & inhibitors
- Urinary Bladder -- cytology
- beta-Cyclodextrins -- pharmacology
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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