The inhibition of activated hepatic stellate cells proliferation by arctigenin through G0/G1 phase cell cycle arrest: persistent p27(Kip1) induction by interfering with PI3K/Akt/FOXO3a signaling pathway. [electronic resource]
Producer: 20151026Description: 71-87 p. digitalISSN:- 1879-0712
- 14-3-3 Proteins -- metabolism
- Active Transport, Cell Nucleus -- drug effects
- Becaplermin
- Cell Line
- Cell Nucleus -- drug effects
- Cell Proliferation -- drug effects
- Cyclin D1 -- metabolism
- Cyclin-Dependent Kinase 4 -- metabolism
- Cyclin-Dependent Kinase 6 -- metabolism
- Cyclin-Dependent Kinase Inhibitor p27 -- metabolism
- Down-Regulation -- drug effects
- Forkhead Box Protein O3
- Forkhead Transcription Factors -- deficiency
- Furans -- pharmacology
- G1 Phase Cell Cycle Checkpoints -- drug effects
- Gene Expression Regulation, Enzymologic -- drug effects
- Gene Knockdown Techniques
- Hepatic Stellate Cells -- cytology
- Humans
- Lignans -- pharmacology
- Phosphatidylinositol 3-Kinases -- metabolism
- Phosphorylation -- drug effects
- Proto-Oncogene Proteins c-akt -- metabolism
- Proto-Oncogene Proteins c-sis -- pharmacology
- RNA, Small Interfering -- genetics
- Resting Phase, Cell Cycle -- drug effects
- Signal Transduction -- drug effects
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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