PBI-05204, a supercritical CO₂ extract of Nerium oleander, inhibits growth of human pancreatic cancer via targeting the PI3K/mTOR pathway. [electronic resource]
Producer: 20160119Description: 271-9 p. digitalISSN:- 1573-0646
- Animals
- Cardiac Glycosides -- pharmacology
- Cell Cycle
- Cell Line, Tumor
- Class Ib Phosphatidylinositol 3-Kinase -- biosynthesis
- Deoxycytidine -- analogs & derivatives
- Down-Regulation
- Female
- Humans
- Mice
- Mice, Inbred BALB C
- Nerium
- Pancreatic Neoplasms -- drug therapy
- Plant Extracts -- pharmacology
- Proto-Oncogene Proteins c-akt -- biosynthesis
- TOR Serine-Threonine Kinases -- biosynthesis
- Gemcitabine
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Publication Type: Journal Article; Research Support, N.I.H., Extramural
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