The effect of UGTs polymorphism on the auto-induction phase II metabolism-mediated pharmacokinetics of dihydroartemisinin in healthy Chinese subjects after oral administration of a fixed combination of dihydroartemisinin-piperaquine. [electronic resource]
Producer: 20150529Description: 478 p. digitalISSN:- 1475-2875
- Administration, Oral
- Adolescent
- Antimalarials -- administration & dosage
- Artemisinins -- administration & dosage
- Asian People
- Chromatography, Liquid
- Drug Combinations
- Glucuronosyltransferase -- genetics
- Healthy Volunteers
- Humans
- Inactivation, Metabolic
- Male
- Plasma -- chemistry
- Polymorphism, Genetic
- Quinolines -- administration & dosage
- Tandem Mass Spectrometry
- Young Adult
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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