Defective mitophagy driven by dysregulation of rheb and KIF5B contributes to mitochondrial reactive oxygen species (ROS)-induced nod-like receptor 3 (NLRP3) dependent proinflammatory response and aggravates lipotoxicity. [electronic resource]
Producer: 20150805Description: 63-71 p. digitalISSN:- 2213-2317
- Animals
- Calcium -- metabolism
- Carrier Proteins
- Gene Expression
- Gene Knockdown Techniques
- Glucose -- metabolism
- Insulin -- metabolism
- Insulin Secretion
- Islets of Langerhans -- drug effects
- Kinesins -- metabolism
- Lipopolysaccharides -- pharmacology
- Mitochondria -- drug effects
- Mitochondrial Membranes -- metabolism
- Mitophagy -- drug effects
- Monomeric GTP-Binding Proteins -- metabolism
- NLR Family, Pyrin Domain-Containing 3 Protein
- Neuropeptides -- metabolism
- Palmitates -- pharmacology
- Protein Transport
- Proteolysis -- drug effects
- Ras Homolog Enriched in Brain Protein
- Rats
- Reactive Oxygen Species -- metabolism
- Receptors, Cytoplasmic and Nuclear -- genetics
No physical items for this record
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
There are no comments on this title.
Log in to your account to post a comment.