Thrombin receptor deficiency leads to a high bone mass phenotype by decreasing the RANKL/OPG ratio. [electronic resource]
Producer: 20150930Description: 14-22 p. digitalISSN:- 1873-2763
- 3T3 Cells
- Animals
- Bone Resorption
- Bone and Bones -- pathology
- Caco-2 Cells
- Calcium -- chemistry
- Femur -- pathology
- Humans
- Male
- Mice
- Mice, Inbred C57BL
- Mice, Knockout
- NF-kappa B -- metabolism
- Osteoblasts -- metabolism
- Osteoprotegerin -- metabolism
- Phenotype
- Polymerase Chain Reaction
- RANK Ligand -- metabolism
- Receptors, Thrombin -- deficiency
- Signal Transduction
- Thrombin -- metabolism
- X-Ray Microtomography
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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