Maslinic acid induces mitochondrial apoptosis and suppresses HIF-1α expression in A549 lung cancer cells under normoxic and hypoxic conditions. [electronic resource]
Producer: 20150716Description: 19892-906 p. digitalISSN:- 1420-3049
- Apoptosis -- drug effects
- Apoptosis Inducing Factor -- metabolism
- Bronchi -- pathology
- Caspase 3 -- metabolism
- Caspase 8 -- metabolism
- Cell Hypoxia -- drug effects
- Cell Line, Tumor
- Cell Survival -- drug effects
- Cytochromes c -- metabolism
- Cytosol -- drug effects
- Epithelial Cells -- drug effects
- Humans
- Hypoxia-Inducible Factor 1, alpha Subunit -- metabolism
- Inhibitor of Apoptosis Proteins -- metabolism
- Lung Neoplasms -- metabolism
- Membrane Potential, Mitochondrial -- drug effects
- Mitochondria -- drug effects
- Nitric Oxide -- metabolism
- Nitric Oxide Synthase Type II -- metabolism
- Reactive Oxygen Species -- metabolism
- Signal Transduction -- drug effects
- Sodium-Potassium-Exchanging ATPase -- metabolism
- Survivin
- Triterpenes -- pharmacology
- bcl-2-Associated X Protein -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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