Assessment of the drug interaction potential and single- and repeat-dose pharmacokinetics of the BRAF inhibitor dabrafenib. [electronic resource]
Producer: 20160314Description: 392-400 p. digitalISSN:- 1552-4604
- Anticoagulants -- pharmacokinetics
- Cytochrome P-450 CYP2C8 Inhibitors -- pharmacology
- Cytochrome P-450 CYP3A Inhibitors -- pharmacology
- Drug Interactions
- Female
- Gemfibrozil -- pharmacology
- Humans
- Imidazoles -- administration & dosage
- Ketoconazole -- pharmacology
- Male
- Middle Aged
- Oximes -- administration & dosage
- Protein Kinase Inhibitors -- administration & dosage
- Proto-Oncogene Proteins B-raf -- antagonists & inhibitors
- Warfarin -- pharmacokinetics
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Publication Type: Controlled Clinical Trial; Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't
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