A loss of antitumor therapeutic activity of CEA DNA vaccines is associated with the lack of tumor cells' antigen presentation to Ag-specific CTLs in a colon cancer model. [electronic resource]
Producer: 20150303Description: 676-85 p. digitalISSN:- 1872-7980
- Animals
- Antibodies, Anti-Idiotypic -- therapeutic use
- Antigen Presentation -- immunology
- Blotting, Western
- CD4-Positive T-Lymphocytes -- immunology
- CD8-Positive T-Lymphocytes -- immunology
- Cancer Vaccines -- therapeutic use
- Carcinoembryonic Antigen -- immunology
- Colonic Neoplasms -- immunology
- Female
- Humans
- Interferon-gamma -- metabolism
- Interleukin-12 -- genetics
- Mice
- Mice, Inbred C57BL
- T-Lymphocytes, Cytotoxic -- immunology
- Tumor Cells, Cultured
- Tumor Necrosis Factor Receptor Superfamily, Member 9 -- immunology
- Vaccines, DNA -- therapeutic use
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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