Resveratrol regulates PTEN/Akt pathway through inhibition of MTA1/HDAC unit of the NuRD complex in prostate cancer. [electronic resource]
Producer: 20150424Description: 265-75 p. digitalISSN:- 0006-3002
- Acetylation -- drug effects
- Animals
- Cell Line, Tumor
- Cell Nucleus -- drug effects
- Down-Regulation -- drug effects
- Enzyme Activation -- drug effects
- Gene Knockdown Techniques
- Histone Deacetylase Inhibitors -- pharmacology
- Histone Deacetylases -- metabolism
- Humans
- Immunoprecipitation
- Male
- Mi-2 Nucleosome Remodeling and Deacetylase Complex -- metabolism
- Mice, Nude
- Models, Biological
- Nucleosomes -- drug effects
- PTEN Phosphohydrolase -- metabolism
- Prostatic Neoplasms -- enzymology
- Protein Binding -- drug effects
- Proto-Oncogene Proteins c-akt -- metabolism
- Repressor Proteins -- antagonists & inhibitors
- Resveratrol
- Signal Transduction -- drug effects
- Stilbenes -- pharmacology
- Trans-Activators
- Up-Regulation -- drug effects
- Xenograft Model Antitumor Assays
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Publication Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.
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