Blau syndrome-associated Nod2 mutation alters expression of full-length NOD2 and limits responses to muramyl dipeptide in knock-in mice. [electronic resource]
Producer: 20160226Description: 349-57 p. digitalISSN:- 1550-6606
- Acetylmuramyl-Alanyl-Isoglutamine -- immunology
- Animals
- Arthritis -- genetics
- Cell Line
- Gene Knock-In Techniques
- HEK293 Cells
- Humans
- Interleukin-6 -- biosynthesis
- Macrophages -- drug effects
- Mice
- Mice, Inbred C57BL
- Mitogen-Activated Protein Kinases -- metabolism
- Mutation
- NF-kappa B -- biosynthesis
- Nod2 Signaling Adaptor Protein -- biosynthesis
- Phosphorylation -- genetics
- Protein Processing, Post-Translational
- RNA Interference
- RNA, Small Interfering
- Receptor-Interacting Protein Serine-Threonine Kinase 2 -- metabolism
- Sarcoidosis
- Signal Transduction -- genetics
- Synovitis -- genetics
- Ubiquitination
- Uveitis -- genetics
- p38 Mitogen-Activated Protein Kinases -- metabolism
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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