Enforced differentiation of Dnmt3a-null bone marrow leads to failure with c-Kit mutations driving leukemic transformation. [electronic resource]
Producer: 20150324Description: 619-28 p. digitalISSN:- 1528-0020
- Animals
- Blast Crisis -- genetics
- Bone Marrow -- enzymology
- Cell Differentiation
- Cell Line
- Cell Transformation, Neoplastic -- genetics
- DNA (Cytosine-5-)-Methyltransferases
- DNA Methyltransferase 3A
- Hematopoiesis -- genetics
- Hematopoietic Stem Cells -- enzymology
- Leukemia, Myeloid, Acute -- enzymology
- Mice
- Mice, Knockout
- Mutation
- Proto-Oncogene Proteins c-kit -- genetics
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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