Targeted delivery of siRNA using transferrin-coupled lipoplexes specifically sensitizes CD71 high expressing malignant cells to antibody-mediated complement attack. [electronic resource]
Producer: 20160621Description: 405-13 p. digitalISSN:- 1776-260X
- Antibodies -- chemistry
- Antigens, CD -- genetics
- CD55 Antigens -- metabolism
- CD59 Antigens -- metabolism
- Cell Line, Tumor
- Complement C3 -- metabolism
- Complement System Proteins
- Down-Regulation
- Female
- Flow Cytometry
- Gene Expression Regulation, Neoplastic
- Humans
- Immunotherapy -- methods
- Male
- Membrane Cofactor Protein -- metabolism
- RNA, Messenger -- metabolism
- RNA, Small Interfering -- metabolism
- Receptors, Transferrin -- genetics
- Transferrin -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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