Darinaparsin inhibits prostate tumor-initiating cells and Du145 xenografts and is an inhibitor of hedgehog signaling. [electronic resource]
Producer: 20150928Description: 23-30 p. digitalISSN:- 1538-8514
- Animals
- Antineoplastic Agents -- administration & dosage
- Arsenicals -- administration & dosage
- Cell Cycle -- drug effects
- Cell Line, Tumor
- Docetaxel
- Dose-Response Relationship, Drug
- Drug Synergism
- Gene Expression Regulation, Neoplastic -- drug effects
- Glutathione -- administration & dosage
- Hedgehog Proteins -- metabolism
- Humans
- Kruppel-Like Transcription Factors -- genetics
- Male
- Mice
- Neoplastic Stem Cells -- drug effects
- Nuclear Proteins -- genetics
- Prostatic Neoplasms -- drug therapy
- Signal Transduction -- drug effects
- Taxoids -- administration & dosage
- Xenograft Model Antitumor Assays
- Zinc Finger Protein Gli2
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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