Pravastatin reverses obesity-induced dysfunction of induced pluripotent stem cell-derived endothelial cells via a nitric oxide-dependent mechanism. [electronic resource]
Producer: 20151228Description: 806-16 p. digitalISSN:- 1522-9645
- Analysis of Variance
- Animals
- Apoptosis -- physiology
- Cell Differentiation
- Diet, High-Fat
- Endothelial Cells -- physiology
- Enzyme Inhibitors -- pharmacology
- Fibroblasts -- physiology
- Hindlimb -- blood supply
- Hydroxymethylglutaryl-CoA Reductase Inhibitors -- pharmacology
- Induced Pluripotent Stem Cells -- physiology
- Injections, Intramuscular
- Ischemia -- physiopathology
- Mice, Inbred C57BL
- Muscle, Skeletal
- Muscular Diseases -- prevention & control
- NG-Nitroarginine Methyl Ester -- pharmacology
- Nitric Oxide -- physiology
- Nitric Oxide Synthase Type III -- metabolism
- Obesity -- physiopathology
- Oxidative Stress -- physiology
- Pravastatin -- pharmacology
- Proto-Oncogene Proteins c-akt -- metabolism
- Random Allocation
- Reperfusion Injury -- physiopathology
- Signal Transduction
No physical items for this record
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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